The FL CHW Coalition was a Y1 Planning Awardee to prepare a 1-hr training curriculum on Precision Medicine and Health Disparities for lay care workers and CHWs, for the Precision Medicine and Health Disparities Collaborative (PMHDC). The curriculum is available in English and Spanish. As defined by the National Research Council, Precision Medicine is the “ability to classify individuals into sub-populations that differ in their susceptibility to a particular disease, in the biology and/or prognosis of the diseases that they may develop, or in their specific treatment.” This Collaborative is a Roadmap providing a diverse group of researchers with the infrastructure and resources to develop collaborative research teams that use precision medicine approaches to eliminate disparities in health outcomes, specifically among African Americans and Latinos.